Episodes

  • Ep. 654 Daily Ayurvedic Self-Care with Dr. Shivani Gupta

    Ep. 654 Daily Ayurvedic Self-Care with Dr. Shivani Gupta
    Oct 14 2026
    Today, I’m delighted to continue my conversation with Dr. Shivani Gupta about curcumin's science and its impact on mitochondrial and brain health. Dr. Gupta is the founder and CEO of Fusionary Formulas and the author of The Inflammation Code. She holds a master's degree and a PhD in Vedic sciences, and her dissertation focused on turmeric's role in inflammation, joint health, and cardiovascular health. In this conversation, we explore Ayurvedic medicine and daily rituals, body types and the five elements, and how they shape how we navigate our lives. We also spend significant time discussing how to find balance in midlife and the rituals Dr. Gupta has found particularly impactful for midlife women. This is another truly invaluable conversation with Dr. Shivani Gupta — one you will most likely want to revisit more than once. IN THIS EPISODE, YOU WILL LEARN: How much turmeric or curcumin you need to take daily to buffer inflammation How curcumin supports the creation of new mitochondria as we age Dr. Gupta explains how Ayurveda uses the Vata, Pitta, and Kapha body types to understand individual differences How trauma or a major change can shift your Ayurvedic constitution The shift toward Vata many women tend to experience during the perimenopause to menopause transition, and how that may show up How to strengthen weak digestive fire Dr. Gupta describes an Ayurvedic morning routine The value of using dry brushing as a simple daily ritual to support circulation and lymphatic flow The benefits of using abhyang massage as an Ayurvedic self-care ritual during menopause How stress and dysregulation affect the vagus nerve Bio: Dr. Shivani Gupta is an Ayurvedic practitioner, turmeric researcher, and founder of Fusionary Formulas. She holds a Master's degree in Ayurvedic Sciences and completed her PhD dissertation on turmeric, making her one of the world's foremost experts on its pharmacology and clinical application. She is the author of The Inflammation Code, published by Hay House, bridging ancient Ayurvedic wisdom with modern inflammation science. Dr. Gupta is known for making complex science accessible without dumbing it down — her work speaks equally to the everyday health-conscious woman and to clinicians who want to go deeper. ***Use the code CYNTHIA for 15% off at FusionaryFormulas.com. Connect with Cynthia Thurlow Follow on X, Instagram & LinkedIn Check out Cynthia’s website. Submit your questions to support@cynthiathurlow.com Join other like-minded women in a supportive, nurturing community: The Midlife Pause/Cynthia Thurlow. Purchase Cynthia’s book, The Menopause Gut. Cynthia’s Intermittent Fasting Transformation Book The Midlife Pause Supplement Line Connect with Dr. Shivani Gupta On her website Use the code CYNTHIA for 15% off at FusionaryFormulas.com Instagram YouTube Facebook Pinterest Fusionary Formulas The Inflammation Code (Book Website) The Inflammation Code Podcast
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    45 mins
  • Ep. 642 Metabolic Health and Brain Aging with Dr. Zaldy Tan | Menopause, Perimenopause, Metabolic Health

    Ep. 642 Metabolic Health and Brain Aging with Dr. Zaldy Tan | Menopause, Perimenopause, Metabolic Health
    Sep 16 2026
    Today, I am honored to connect with Dr. Zaldy Tan, a geriatric medicine and memory disorder specialist whose research career has centered on the Framingham Heart Studies Offspring Cohort. Dr. Tan currently directs Cedar Sinai’s memory and healthy aging programs, after previously leading the memory clinic at Beth Israel and Harvard Medical School. His book, Age Proof Your Mind, translates his clinical and research background into a practical framework for people trying to assess and protect their own cognitive trajectory. In our conversation, Dr. Tan explains why middle age is the old age of youth and the youth of old age. We discuss common symptoms of memory issues and those that are reversible. We explore the Framingham Offspring Study and its impact on brain health over time, looking at the effects of sleep, depression, vitamin deficiencies, alcohol, loneliness, and nutrition, and Dr. Tan shares the three Ds, dementia, delirium, and depression- the red flags he sees in his clinical practice, explains how he helps prepare caregivers for caring for loved ones with neurocognitive memory loss, and discusses late-stage issues, medications, blood-based biomarkers, and the role of genetics in brain health. Stay tuned for a truly fascinating discussion with Dr. Zaldy Tan. IN THIS EPISODE, YOU WILL LEARN: The importance of being sensitive to how your memory changes over time Various factors that could contribute to memory problems The profound effect alcohol has on the brain and neurologic function How social isolation can increase the risk of dementia in future years Dr. Tan discusses the Framingham Offspring Study and the links between metabolic dysregulation and brain MRI markers of brain aging. How the 3 Ds, delirium, dementia, and depression, can overlap The red flags in a patient’s history that lead Dr. Tan to believe there may be a more serious issue What care partners should be aware of when a family member is experiencing dementia The importance of protecting sleep and maintaining consistent sleep patterns for those with memory problems How genetic testing is incorporated into Dr. Tan’s care model Bio: Dr. Zaldy Tan is the Director of the Memory & Healthy Aging Program at Cedars-Sinai Medical Center, which U.S. News & World Report ranked in 2024 as the best hospital on the U.S. West Coast and among the top hospitals in the country. He holds the Carmen & Louis Warschaw Endowed Chair in Neurology and is a professor at the David Geffen School of Medicine, University of California, Los Angeles. Dr. Tan was the founding director of the Memory Disorders Clinic at Harvard Medical School/Beth Israel Deaconess Medical Center. Dr. Tan performs aging and dementia research covered by The New York Times, Time, CNN, The Wall Street Journal, NPR, The Washington Post, The Chicago Tribune, Reuters, ABC News, and NBC News. He regularly speaks at major national and international conferences and is the author of Age-Proof Your Mind and What to Remember When You Are Forgetting. Connect with Cynthia Thurlow Follow on X, Instagram & LinkedIn Check out Cynthia’s website. Submit your questions to support@cynthiathurlow.com Join other like-minded women in a supportive, nurturing community: The Midlife Pause/Cynthia Thurlow. Purchase Cynthia’s book, The Menopause Gut. Cynthia’s Intermittent Fasting Transformation Book The Midlife Pause Supplement Line Connect with Dr. Zaldy Tan Dr. Tan at Cedars Sinai (Los Angeles) On Instagram Dr. Tan’s book, What to Remember When You Are Forgetting, is coming out on September 15th, 2026. Pre-order HERE.
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    44 mins
  • Ep. 631 The Metabolic Health Masterclass | Menopause, Perimenopause, Metabolic Health

    Ep. 631 The Metabolic Health Masterclass | Menopause, Perimenopause, Metabolic Health
    Aug 19 2026
    Today, we have a metabolic health masterclass, featuring Dr. Robert Lustig, Ben Azadi, Dr. Ben Bikman, Mark Sisson, and Dr. Nick Norwitz. In today’s masterclass, we explore why metabolic dysfunction is not simply a calories-in, calories-out issue or a failure of willpower, how insulin and leptin influence appetite and behavior, how early signs of insulin resistance can appear years before a diabetes diagnosis, and the important relationship between muscle, glucose regulation, and insulin sensitivity. We also discuss how movement supports fat burning without sacrificing muscle, why chronic cardio may not produce the results many people expect, and how emerging technology could provide a far more personalized approach to metabolic care. Stay tuned for today’s informative discussion, where our panel of experts shares their valuable perspectives on metabolic health. IN THIS EPISODE, YOU WILL LEARN: Leptin resistance and how it can drive the overeating and inactivity commonly associated with obesity How elevated insulin blocks the effects of leptin Why it’s essential to pay attention to fasting insulin rather than waiting for blood glucose to rise Ben Azadi highlights metabolic health markers that can provide information beyond fasting glucose. How our muscles help to regulate glucose and support insulin sensitivity The importance of building and preserving muscle to support insulin sensitivity as we age, and how even a brief period of inactivity can reduce insulin sensitivity Mark Sisson explains why running may not be the most effective fat loss strategy How walking can increase your fat-burning capacity while also helping to preserve your muscles Dr. Nick Norwitz explains how type 2 diabetes can involve different underlying pathologies, and how CGM data and machine learning can eventually help to identify specific subphenotypes Connect with Cynthia Thurlow Follow on X, Instagram & LinkedIn Check out Cynthia’s website. Submit your questions to support@cynthiathurlow.com Join other like-minded women in a supportive, nurturing community: The Midlife Pause/Cynthia Thurlow. Purchase Cynthia’s book, The Menopause Gut. Cynthia’s Intermittent Fasting Transformation Book The Midlife Pause Supplement Line Connect with Dr. Robert Lustig Website On Facebook, Instagram, and Twitter Connect with Ben Azadi Website On Instagram, Facebook, LinkedIn, YouTube, TikTok Get a copy of Ben Azadi’s latest book, Metabolic Freedom. Connect with Dr. Ben Bikman Website On social media: @benbikmanphd Connect with Mark Sisson Mark’s book, Born To Walk Peluva Shoes Connect with Nick Norwitz On YouTube, X, and Instagram His Substack Previous Episodes: Ep. 161 Robert Lustig & Cynthia Thurlow Discussing The Nutritional Battlefield & Debunking Chronic Diseases Ep. 465 Metabolic Health 101: Fat Loss, Toxins, and Seed Oils with Dr. Ben Azadi Ep. 316 The Impact of Age, Gender and Lifestyle on Metabolic Health with Dr. Ben Bikman Ep. 422 Walking for Health: The Underrated Exercise You Need with Mark Sisson Ep. 525 We’ve Been Misled About Metabolic Health – The Shocking Truth About Cholesterol, GLP-1 & Aging with Dr. Nick Norwitz
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    1 hr and 1 min
  • BONUS: Peri/Menopause are a Natural Function of Aging: See you later, Ovulator! with Esther Blum

    BONUS: Peri/Menopause are a Natural Function of Aging: See you later, Ovulator! with Esther Blum
    Jul 1 2024
    I am honored to connect with Esther Blum today! She is the bestselling author of "Cavewomen Don’t Get Fat," "Eat, Drink, and Be Gorgeous," and most recently, "See Ya Later, Ovulator!". Esther currently maintains a busy virtual practice where she helps women balance hormones, lose stubborn body fat, and treat the root cause of health struggles. Today we speak about medical gaslighting, how weight gain does not have to be a part of aging, andropause and menopause, and the Women’s Health Initiative. We dive into physical changes and significant symptoms during perimenopause and menopause, the role of the pelvic floor, deciphering what the dreaded “menopot” is, what does not work, and advocacy in terms of testing and hormones. We also address constipation, weight loss resistance, and how our tolerance for alcohol changes as we age, especially when using bioidenticals or hormone replacement therapy. IN THIS EPISODE YOU WILL LEARN: How women can redefine their experience and continue having an active sex life after menopause. How to surrender, lean in, and take the pressure off yourself while going through perimenopause and menopause. Why is there so much misinformation and medical gaslighting in our society? Why Esther wrote See Ya Later, Ovulator! Some common symptoms of perimenopause. Risks women may face after a hysterectomy. Changes that happen in the vaginal canal and pelvic floor during menopause. The significant and profound impact of the decline of sex hormones. How to avoid weight gain in menopause. What can menopausal women do to prevent fatty liver and digestive problems? Lab tests women should be asking their health providers for. Why should perimenopausal women avoid alcohol? Some simple ways to address constipation. Connect with Cynthia Thurlow Follow on Twitter, Instagram & LinkedIn Check out Cynthia’s website Connect with Esther Blum On her website On Facebook, Instagram, LinkedIn Get your free copy of Esther’s Happy Hormone Cocktail Esther’s Books Esther’s book, See Ya Later, Ovulator!, by Esther Blum Cavewomen Don’t Get Fat, by Esther Blum Eat, Drink, and Be Happy, by Esther Blum
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    1 hr and 1 min
  • Ep. 374 Understanding Visceral Fat and Its Impact on Health with Dr. Sean O'Mara

    Ep. 374 Understanding Visceral Fat and Its Impact on Health with Dr. Sean O'Mara
    Jun 29 2024
    Today, I am honored to connect with Dr. Sean O'Mara, the leading global health and performance-optimizing physician. Dr. O'Mara is a former ER physician and attorney. He works with business executives, professional performers, and athletes, and he has also had the chance to collaborate with multiple United States presidents, Secretaries of State, senior government officials, and high-level foreign dignitaries. In our discussion today, we address the dangers of visceral fat and the general lack of awareness of it, particularly among healthcare professionals. We cover various types of fat, the influence of Big Pharma, and the impact of menopause on disease susceptibility. We dive into health optimization, sarcopenia, sarcopenic obesity, frailty, adiponectin, and MRIs for assessing visceral fat, and Dr. O'Mara offers valuable insights on muscle tissue differences, lifestyle factors, epigenetics, and the most effective exercises, discussing his advocacy for intermittent fasting, the importance of clinical labs, and the specific supplements for managing visceral fat. He also shares his thoughts on alcohol and caffeine. This engaging and informative episode with Dr. Sean O’Mara features numerous slides and MRI images. So, I recommended viewing it on YouTube. IN THIS EPISODE YOU WILL LEARN: Why visceral fat is a significant contributor to chronic disease How visceral fat invades muscles, leading to the loss of spinal erectness Why superficial subcutaneous fat is essential for health The impact of visceral fat on muscle mass and bone density in older adults How lifestyle choices impact metabolic health The benefits of fermented foods and extended fasting for optimal health Why Dr. O’Mara believes that modern humans are less intelligent than our ancestors How fasting helps to cleanse the body and reverse disease How distance running and cycling can impact the body negatively, and the benefits of sprinting Why Dr O’Mara recommends avoiding alcohol Connect with Cynthia Thurlow Follow on Twitter Instagram LinkedIn Check out Cynthia’s website Submit your questions to support@cynthiathurlow.com Connect with Dr. Sean O'Mara On his website Instagram YouTube TikTok LinkedIn Join Dr. O’Mara’s online community (www.drseanomara.podia.com) Recommended Podcast What Alcohol Does to Your Body, Brain & Health, from Andrew Huberman
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    1 hr and 19 mins
  • Ep. 373 Mastering Supplement Quality: A Comprehensive Guide with Shawn Wells

    Ep. 373 Mastering Supplement Quality: A Comprehensive Guide with Shawn Wells
    Jun 26 2024
    I am delighted to have Shawn Wells, affectionately known as the Ingredientologist, joining me again today. Shawn is a leading nutritional biochemist and health optimization expert. He is also a biohacker and the formulator of over 500 supplements, foods, beverages, and cosmeceuticals. In our conversation today, we cover how to evaluate the quality of supplements, explain what proprietary blends represent, and explore several exciting new supplements like Peptide 185, Paraxanthine, and various nootropic agents. Shawn shares his optimal supplement stacks for sleep, metabolism, gut health, and regulating blood sugar, diving into the impact of delivery systems, including transdermal approaches and IV therapies. He also offers guidance on setting intentions and affirmations around supplement consumption. I trust that you will find this conversation with Shawn Wells as enjoyable and informative as I did while recording it. IN THIS EPISODE YOU WILL LEARN: Shawn shares his concerns about quality control in supplement manufacturing. Why it is essential to buy supplements only from trusted brands when ordering from big retailers Shawn discusses the potential benefits of the new supplement, Peptide 185, for muscle protein synthesis. The potential leucine holds for age-related muscle loss and sports nutrition. Shawn dives into the physical effects of the caffeine metabolite paraxanthine. BDNF-boosting ingredients for neuroplasticity and brain protection How adaptogenic herbs can increase resilience and improve sleep quality, energy, and focus Shawn highlights the importance of physical movement and proper posture for maintaining physical health. How a leaky gut can lead to immunological problems and cognitive impairment Shawn explores the effectiveness of supplementation versus methods like high-intensity interval training for boosting NAD levels. Shawn explains how to use intention and affirmations to maximize the absorption of supplements. Bio: Shawn Wells: Shawn Wells MPH, LDN, RD, CISSN, FISSN is the world’s leading nutritional biochemist and expert on health optimization. Meet the Ingredientologist, a visionary scientist behind over 1000 groundbreaking formulations, including 25 patented ingredients like Paraxanthine, Teacrine, Dynamine, and Dihydroberberine. Once a Chief Clinical Dietitian, he has empowered thousands with innovative health solutions like keto, paleo, fasting, and supplements, overcoming his own battles with Epstein-Barr Virus, Chronic Fatigue Syndrome, and more. As a world-renowned thought leader on mitochondrial health, he has spoken on five continents and featured in acclaimed documentaries and podcasts. Discover his practical, research-backed solutions in "The ENERGY Formula," hailed by USA Today, Forbes, and an Amazon best-seller. Experience greater resilience and boundless energy under his expert guidance. Connect with Cynthia Thurlow Follow on Twitter Instagram LinkedIn Check out Cynthia’s website Submit your questions to support@cynthiathurlow.com Connect with Shawn Wells On his website Shawn’s biohacking book, The Energy Formula On Instagram, YouTube, Facebook, LinkedIn, Twitter, Pinterest, and TikTok Previous Episode Mentioned Ep. 126 – Plant Medicine: Bio-Hacking Your Way to Optimum Health featuring Shawn Wells
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    1 hr and 15 mins
  • BONUS: Rethinking Diabetes: Treatment and Management in the Modern Era with Gary Taubes

    BONUS: Rethinking Diabetes: Treatment and Management in the Modern Era with Gary Taubes
    Jun 24 2024
    I am thrilled to have Gary Taubes back on the show today. (He was with me before on episode 137. Gary is an investigative science and health journalist whose work has been pivotal in catalyzing the low-carb keto movement. He has written many books, including his most recent, Rethinking Diabetes, and his articles are in many of the best anthologies. He has also received many science awards. Today's discussion is particularly significant, given the recent report from the American Diabetes Association revealing that the annual cost of diabetes in the United States reached a staggering $412.9 billion in 2022, with individuals diagnosed with diabetes now representing one in every four dollars spent on healthcare. In our discussion today, we dive into the history of diabetes, pertinent statistics, the prevailing standard of care, and the transformative influence of insulin on diabetes management and reactive hypoglycemia. Gary provides insights into his reactions to GLP ones, the integration of medical and nutrition science into the medical field, and the influence of organizations such as the American Diabetes Association, AHA, USDA, and NIH. Our discussion also extends to the effects of pharmaceuticals, the shortcomings in our approach to diabetes management and existing models, and the challenge the low-carb community faces. Stay tuned for today's eye-opening conversation, where we shed light on the complexities surrounding diabetes care, explaining how simple lifestyle changes can tremendously improve quality of life. IN THIS EPISODE YOU WILL LEARN: Rethinking Diabetes is a groundbreaking exploration of diabetes diagnosis, management, and treatment Gary discusses the evolution of evidence-based medicine Why the traditional medical approach to treating diabetes is inadequate How the guidelines of the American Diabetes Association were based on outdated assumptions How medical treatments compare with lifestyle changes for managing diabetes Controversies surrounding how the pharmaceutical industry has influenced the way medical associations have shaped their diabetes management policies How medical guidelines and dietary advice have evolved What constitutes a healthy diet? How patients often have trouble following diet recommendations, despite their best intentions Is obesity a hormonal disorder or caused by overeating? Connect with Cynthia Thurlow Follow on Twitter Instagram LinkedIn Check out Cynthia’s website Submit your questions to support@cynthiathurlow.com Connect with Gary Taubes On his website Twitter Facebook Previous Episode Mentioned: Ep. 137 – High Blood Sugar Levels And Its Long-Term Damage with Gary Taubes Book Mentioned: Rethinking Diabetes What Science Reveals About Diet, Insulin, and Successful Treatments is available from most bookstores or on Amazon.
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    59 mins
  • Ep. 372 Metabolism Repair for Women: Strategies and Insights with Dr. Lara Briden

    Ep. 372 Metabolism Repair for Women: Strategies and Insights with Dr. Lara Briden
    Jun 22 2024
    Today, I am thrilled to reconnect with one of my favorite physicians, Dr. Lara Briden, a naturopathic doctor specializing in women's health. Dr. Briden is on a mission to help women achieve natural menstrual cycles without relying on hormonal birth control. She has authored several books, including her latest, Metabolism Repair for Women. In our conversation today, we dive into why we cannot consciously control energy balance, the impact of ultra-processed foods, epigenetic factors in obesity, the significance of satiety hormones, the role of muscle, and the effects of visceral fat versus subcutaneous fat. We also discuss ways to assess metabolic health and explore various treatments. This insightful discussion with Dr. Lara Briden is bound to captivate and inform all our listeners. Stay tuned for more. IN THIS EPISODE YOU WILL LEARN: Why energy balance is not under our conscious control How the regulatory mechanism in the body naturally reduces hunger and burns energy How ultra-processed foods were created to be addictive and lead to overeating How the adiponectin hormone impacts insulin sensitivity and satiety The importance of maintaining muscle mass and avoiding sarcopenia, particularly during menopause The difference between subcutaneous and visceral fat Measuring and managing visceral fat How High triglycerides often indicate insulin resistance The limitations of the fasting insulin test Using the entrainment of circadian rhythm to improve metabolic health The benefits of addressing gut problems for improving metabolic health Connect with Cynthia Thurlow Follow on Twitter Instagram LinkedIn Check out Cynthia’s website Submit your questions to support@cynthiathurlow.com Connect with Dr. Lara Briden On her website On social media: @Lara Briden Dr. Briden’s latest book is titled The Metabolism Reset in Australia and New Zealand. Everywhere else, it is titled Metabolism Repair for Women Other Books by Dr. Briden Period Repair Manual Hormone Repair Manual Previous Episode Mentioned Ep. 220: A Detailed Guide to Healthy Hormones with Dr. Lara Briden
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    54 mins