• #21 Pt1: Ocean Wave, Avalanche or Volcano? 40 Years of Female Orgasm Science
    Sep 15 2026
    Send us Fan MailAnna Lee, CEO and co-founder of Lioness, joins Judith to reveal what a dataset of around 100,000 orgasms has uncovered about female sexual pleasure — and how little the science had actually established before. This part covers how the Lioness biofeedback vibrator measures involuntary pelvic-floor contractions, the three distinct orgasm patterns the data reveals, and the finding that will genuinely surprise most listeners: orgasm strength tends to increase as women move into their fifties and sixties, not decline.Key topics discussed- What the Lioness device actually measures, and how biofeedback orgasm data works- The three orgasm patterns — ocean wave (rhythmic, most common), avalanche (high force tapering down), and volcano (rare, single explosive peak) — identified through involuntary pelvic-floor contractions- Why those patterns matter: correcting four decades of incomplete research based on a 1982 study of only 11 women- The type-switching debate: whether a person moves between orgasm patterns over time, and what the current data does and does not show- The age finding: women aged 51–60 appear to reach orgasm fastest and generate the strongest peak force — contradicting the widespread assumption that sexual pleasure declines with age- Why this podcast cares: the knowledge gap in female sexual health, and how understanding your own body is a health act, not a vanity oneTimestampsThese are estimates and may shift in final editing.0:00 — Introduction: Judith introduces Anna Lee and Lioness1:00 — What Lioness measures: involuntary pelvic-floor contractions during pleasure and orgasm2:30 — How the app works: pairing the device, reading the data, tracking lifestyle factors4:00 — The three orgasm patterns: ocean wave, avalanche, volcano6:30 — The 1982 Bohlen study (n=11) versus the Lioness dataset (~100,000 data points); the Pfaus/Hartmann research8:30 — The type-switching debate: do people move between patterns?10:00 — The age study: orgasm strength increases in the 51–60 range12:30 — Why this matters: "knowledge is pleasure," and the parallel to tracking sleep and nutrition14:00 — Fertility and orgasm type: what we do and do not know15:30 — End of Part 1ReferencesLioness Smart VibratorThe biofeedback device discussed throughout. Measures involuntary pelvic-floor contractions during pleasure and orgasm and displays the data via paired smartphone app.https://lioness.ioPfaus J, Hartmann D, Wood E, Wang J, Klinger E. "Women's Orgasms Determined by Autodetection of Pelvic Floor Muscle Contractions Using the Lioness 'Smart' Vibrator."The Journal of Sexual Medicine, 2022, Vol 19, Suppl 3. Led by Dr. Jim Pfaus of Charles University, Prague. The study defining the three orgasm patterns (ocean wave, avalanche, volcano) using the Lioness dataset; approximately 37–40 participants.https://academic.oup.com/jsm/article-abstract/19/Supplement_3/S2/7012773Hartmann D, Pfaus J, Wood E, Klinger L, Wang J. "Are All Orgasms Created Equally Regardless of Age?"The Journal of Sexual Medicine, 2023, Vol 20, Suppl 2. Led by Dee Hartmann, pelvic-floor therapist. Study of 26 women aged 21–60 showing that women aged 51–60 reached orgasm fastest and generated the strongest peak force (~1,425 gm/f).https://academic.oup.com/jsm/article/20/Supplement_2/qdad061.034/7165577Bohlen JG et al. "The Female Orgasm: Pelvic Contractions."Archives of Sexual Behavior, 1982. The original study identifying different orgasm contraction patterns in 11 women. The foundational paper that the Lioness research builds on and substantially extends.[No URL — print publication; flag for editorial review if a DOI link is required]Dr. Jim PfausResearcher at Charles University, Prague. Led the orgasm-pattern classification study using Lioness data.Dee HartmannPelvic-floor therapist based in the United States. Led the age and orgasm-strength study using Lioness data. Also mentioned in connection with the Kegel/pelvic-floor research (covered in Part 2).Guest links and socialsAnna Lee, CEO and co-founder of LionessLioness website: https://lioness.ioLioness Instagram: @lionesshealthLioness LinkedIn: https://www.linkedin.com/company/lionesshealthAnna Lee personal Instagram: @annaisaverageAnna Lee personal LinkedIn: https://www.linkedin.com/in/annakleeLioness app: available on iOS and Android — search 'Lioness' in the App Store or Google PlayInsta/TikTok: @BiohackingEveWebsite: www.BiohackingEve.com
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    15 mins
  • #21 Pt2: Caffeine, THC, Alcohol - What Actually Changes Your Orgasm
    Sep 15 2026
    Send us Fan MailPart 2 of Judith's conversation with Anna Lee, CEO and co-founder of Lioness, gets into the practical side: what actually changes your orgasms, and what the data shows. Anna walks through the findings from Lioness's Sexperiments platform — including why edging outperforms everything else tested by a significant margin, why alcohol consistently weakens orgasms, and what the THC data looks like. She also corrects the most common misunderstanding about Kegel exercises, explains how a sports concussion showed up as flatlined orgasm data before anyone knew what to look for, and makes the case that female sexual dysfunction could be an early signal of broader health problems — in the same way erectile dysfunction flags cardiovascular risk.KEY TOPICS DISCUSSED— Sexperiments platform: how Lioness runs collective experiments with users and analyses aggregated data— Edging: what it is, why it produces the largest measurable effect on orgasm intensity and duration of anything tested, and how sessions typically run three to four times longer— Alcohol, THC, CBD, caffeine, and socks: what the data shows for each— The concussion case study: how a flatlined orgasm pattern in an elite athlete pointed to neurological impact rather than a broken device, and why this matters clinically— Sexual dysfunction as a potential early-warning signal: the parallel to erectile dysfunction and cardiovascular disease— Kegels, corrected: why pelvic-floor health is built on muscle relaxation as much as contraction, and why the bicep-curl analogy changes how you think about it— Involuntary orgasmic contractions vs voluntary Kegel contractions: preliminary data suggesting masturbation may be a more effective pelvic-floor workout than Kegels alone (note: study is at abstract stage, not yet published)— Cycle tracking: the gap in the current Lioness dataset, and why tagging cycle phase into the data matters— Integrations on the horizon: Oura ring heart rate and stress data, period and fertility tracking apps, EEG consumer monitors, and vaginal moisture monitoring (Kegg)— How Lioness differs from other vibrators: design choices made specifically for female bodies, including insertable length, platinum-cure silicone, low-battery indicator, and travel lock— The full shape of the clitoris: how recently this was understood, and why it changes how we categorise orgasm types— The nerve-fibre correction: why the widely-cited 7,000–8,000 figure came from a cow sample, and what Dr. Blair Peters's 2023 human study actually found— The cultural shift in female sexual wellness: what has changed in nine years, what is still lagging, and the billboard censorship story— Anna's "magic pill" answer: why the most effective single thing is knowledge of your own body, not a product— Book recommendations: Bonk by Mary Roach and The Toaster Project by Thomas ThwaitesTIMESTAMPSThese are estimates and may shift in final editing.0:00 — Introduction to Part 2 / transition from Part 10:30 — Sexperiments platform: what it is and how it works2:30 — Edging: definition, why it outperforms all other tested variables5:00 — Alcohol, THC, CBD, caffeine effects on orgasm data; socks myth debunked9:00 — The concussion case study: athlete's flatlined data and the neurological connection11:30 — Sexual dysfunction as potential early health signal; the erectile dysfunction parallel13:00 — Kegels corrected: the bicep-curl analogy, relaxation vs squeezing, fast-twitch and slow-twitch muscles15:30 — Preliminary data: involuntary orgasmic contractions vs voluntary Kegel contractions; masturbation and pelvic-floor strength (abstract stage)17:00 — Cycle tracking gap; the IUD oversight; new tagging feature in the Lioness app18:30 — Integrations: Oura, period tracking, EEG monitors, Kegg moisture data20:00 — Lioness vs other vibrators: design decisions, insertable size, silicone safety, travel lock22:00 — The full clitoris shape and the nerve-fibre correction (Dr. Blair Peters, 10,281 fibres; cow-sample origin of the old figure)24:00 — Cultural shift: what has changed in nine years; social media policies; the billboard censorship story27:00 — Anna's "magic pill" thesis: why knowing your own body is the answer29:00 — Book recommendations: Bonk and The Toaster ProjectREFERENCESLioness Sexperiments platformhttps://lioness.io"Are All Orgasms Created Equally Regardless of Age?" — Hartmann D, Pfaus J, Wood E, Klinger L, Wang JThe Journal of Sexual Medicine, 2023, Vol 20, Suppl 2. Age-stratified study of 26 women (ages 21–60) using Lioness biofeedback data; women aged 51–60 reached orgasm fastest and generated the strongest peak contractile force (~1,425 gm/f).https://academic.oup.com/jsm/article/20/Supplement_2/qdad061.034/7165577"Women's Orgasms Determined by Autodetection of Pelvic Floor Muscle Contractions Using the Lioness 'Smart' Vibrator" — Pfaus J, Hartmann D, Wood E, Wang J, Klinger EThe Journal of ...
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    29 mins
  • #23 Pt2: Skeleton in the Closet - The Tests, Tech and Nutrition That Actually Build Stronger Bones
    Sep 1 2026

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    Gary Rhodes of Screen My Bones gets practical in Part 2: which bone scans are available, what they measure, and how often to retest. He explains the science behind osteogenic loading and BioDensity — a technology that builds bone safely even in people with severe osteoporosis — and covers what someone with no gym access can do. The episode also covers the specific nutrition that supports bone density, including the calcium-K2 relationship that most people get wrong.

    Key topics:
    DEXA scan: T-score, Z-score, fragility score, TBS, radiation, inaccuracy rate
    EchoLight (REMS ultrasound): bone density + quality, no radiation, 5-year risk window
    Why the TBS function on DEXA machines is rarely used — and why it matters
    Retest frequency: every 12 months recommended vs NHS 3-year standard
    BioDensity and osteogenic loading: the science, the safety, Wolff's Law
    Power Plate (whole-body vibration) and the Rev Bike (vibration + VO2 max)
    Impact vs loading: what each does for bone and whether you need both
    Zero-budget bone-building: running, hopping, jumping, heavy lifting
    Why cyclists, swimmers, and rowers have unexpectedly poor bone density
    EMS (electro-muscular stimulation): role and limitations
    Results: bone quality and T-score changes in 6 and 18 months
    Nutrition: whole foods, protein, absorption, eating in parasympathetic state
    Specific nutrients: D3 + K2/MK-7, magnesium, collagen, boron, Omega-3
    Calcium supplementation: why it can cause harm without K2 and exercise
    Protein and bone: the muscle-bone connection

    References and resources mentioned:
    EchoLight / REMS ultrasound technology
    BioDensity — Performance Health Systems
    Power Plate — Performance Health Systems
    Rev Bike — Performance Health Systems
    eGym (variable resistance training technology)
    Dr Vonda Wright — Unbreakable
    Dr Gabrielle Lyon — creatine research
    Wolff's Law (foundational bone remodelling principle — medical school curriculum)

    Guest social links:
    Website: screenmybones.com
    Instagram (Gary Rhodes): https://www.instagram.com/garyandrewrhodes/
    Instagram (Screen My Bones): https://www.instagram.com/screenmybones?igsh=MWY0ZWc1OWY1OGhubw==
    Instagram (Screen My Bones US): https://www.instagram.com/screenmybones.us/
    Instagram (Performance Health MSK): https://www.instagram.com/performancehealthsystemsmsk/
    Facebook (Screen My Bones): https://www.facebook.com/profile.php?id=61566125690406
    Facebook (Performance Health MSK): https://web.facebook.com/PerformanceHealthSystemsMSK

    Insta/TikTok: @BiohackingEve
    Website: www.BiohackingEve.com

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    23 mins
  • #23 Pt1: Skeleton in the Closet - GLP-1s, Stress and Why Bone Loss Starts Decades Before You Expect
    Aug 18 2026

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    Gary Rhodes, founder of Screen My Bones, opens a three-part deep dive into the most overlooked pillar of women's longevity: skeletal health. Part 1 covers what osteoporosis and osteopenia actually are, why bone loss in women accelerates so dramatically at menopause, and the hidden risks from GLP-1 weight loss drugs, chronic stress, and emotional trauma. Gary reversed his own grandmother's severe osteoporosis in 23 months — and has since scanned over 20,000 people to build the evidence base for early, proactive bone screening.

    Key topics:
    Reversing osteoporosis: Gary's grandmother's story (T-score minus 2.7 → normal range in 23 months)
    What osteoporosis is — and why "disease" is the wrong framing
    Bone density vs bone quality — two distinct measurements, both essential
    T-scores, Z-scores, fragility scores: what to pay attention to
    The menopause bone cliff: 1–5% loss per year, up to 20% over 5–7 years
    Why women lose bone faster than men (oestrogen mechanism)
    Osteoporosis prevalence: 19.6% in women vs 4.4% in men over 50
    Peak bone mass at 28–32 and the case for screening in your thirties
    GLP-1 drugs (Ozempic, Mounjaro) and the 40% muscle/bone loss risk
    Osteoimmunology: bone marrow as immune factory; inflammatory cytokines and bone resorption
    Cortisol, adrenal stress and mineral depletion from bone
    Emotional trauma as a bone health risk factor

    References and resources mentioned:
    Screen My Bones: screenmybones.com
    Tony Robbins — Unleash the Power Within (UPW): https://www.tonyrobbins.com/events/unleash-the-power-within
    Dr Gabrielle Lyon — creatine and muscle protein research

    Guest social links:
    Website: screenmybones.com
    Instagram (Gary Rhodes): https://www.instagram.com/garyandrewrhodes/
    Instagram (Screen My Bones): https://www.instagram.com/screenmybones?igsh=MWY0ZWc1OWY1OGhubw==
    Instagram (Screen My Bones US): https://www.instagram.com/screenmybones.us/
    Instagram (Performance Health MSK): https://www.instagram.com/performancehealthsystemsmsk/
    Facebook (Screen My Bones): https://www.facebook.com/profile.php?id=61566125690406
    Facebook (Performance Health MSK): https://web.facebook.com/PerformanceHealthSystemsMSK

    Insta/TikTok: @BiohackingEve
    Website: www.BiohackingEve.com

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    35 mins
  • #22 Pt2: How Microplastics End Up in Vaginal Tissue
    Aug 4 2026

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    In Part 2, materials engineer Shagun Maheshwari unpacks what conventional menstrual pads are actually made of — up to 90% plastic — and what that means for the body and the environment. Phthalates, microplastics, greenwashing, and why she designed Papaya to degrade in a landfill, not just a composter.

    Key topics in this part:
    - Why conventional pads can be up to 90% plastic; heat-bonding and textile engineering
    - Adhesives as a still-unsolved sustainability problem
    - Phthalates and VOCs; endocrine disruption and absorbent vulvovaginal tissue
    - Why fragrance can worsen period odour rather than mask it
    - Antimicrobial properties and the delicate vaginal microbiome balance
    - Microplastics vs nanoplastics, and how they reach tissue
    - Why plastic doesn't biodegrade; what genuine biodegradability requires
    - Greenwashing: "biodegradable top sheet," bamboo/cotton pads that still contain SAP, the label test
    - Industrial composter vs landfill degradation standards
    - Lifetime product volume (≈5,000–15,000 products); ~800-year SAP degradation
    - Where to find Papaya; what's next for the product
    - The case for putting people who experience the problem on the technical design team

    Timestamps:
    00:00 — Hookable intro
    00:42 — Biohacking Eve intro
    01:07 — Recap of Part 1
    01:27 — Episode summary
    02:27 — Conversation resumes: plastics in pads
    08:00 — Endocrine disruptors, fragrance, microbiome
    16:00 — Microplastics and how they reach tissue
    22:00 — Why plastic doesn't biodegrade; greenwashing and the label test
    28:00 — Composter vs landfill; lifetime volume
    33:00 — Where to find Papaya
    34:00 — Curveball questions
    40:00 — Close → outro

    References mentioned in this part:
    - Super absorbent polymer / sodium polyacrylate (SAP); polyacrylate, polypropylene, polyurethane
    - Phthalates; volatile organic compounds (VOCs)
    - Industrial composting vs landfill degradation standards (≈90% in six months)
    - Strange Pictures by Uketsu — Japanese mystery novel
    - Agatha Christie; P.G. Wodehouse (Jeeves and Wooster); Joseph Campbell (the hero's journey)

    Guest & product links:
    Website: papayapads.com
    Instagram: @papaya.india and @shagun.maheshwari
    LinkedIn (Shagun): https://www.linkedin.com/in/maheshwarishagun/
    LinkedIn (company): https://www.linkedin.com/company/papayaindia/
    Pilots in other countries: bulk orders only — contact Shagun directly


    Insta/TikTok: @BiohackingEve
    Website: www.BiohackingEve.com

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    38 mins
  • #22 Pt1: The Four Layers Inside a Supermarket Pad
    Jul 21 2026

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    Materials engineer Shagun Maheshwari spent five years building the world's first blood-coagulating menstrual pad. In Part 1, she explains why the industry tests pads against saline rather than blood, takes a conventional pad apart layer by layer, and reveals the reframe — keep dry, don't just absorb — that led to a pad which clots blood in place.


    Key topics in this part:

    • Why pads are tested against water/saline, and how menstrual blood differs
    • The four-layer anatomy of a conventional pad (top sheet, ADL, core, back sheet)
    • Super absorbent polymer (SAP) and why it collapses under body weight
    • The reframe from "absorb more" to "keep the person dry"
    • How a physical, charge-based clot works (vs the biological clotting cascade)
    • The naturally derived long-chain sugar coagulant, and how it was found
    • Whether some "period problems" are actually product-design problems
    • Industry inertia around cheap, mass-produced SAP


    Timestamps:

    • 00:00 — Hookable intro
    • 00:40 — Biohacking Eve intro
    • 01:05 — Episode summary
    • 02:05 — Conversation begins: from smart contact lenses to period pads
    • 07:00 — Optimising for the wrong metric; periods vs product problems
    • 14:00 — What's in blood, and why it's hard to engineer for
    • 16:00 — Pad anatomy, layer by layer
    • 20:00 — Why fluid comes back out under load
    • 21:00 — How coagulation works inside Papaya's pad
    • 28:00 — The coagulant material and how it was identified
    • 31:00 — Cliffhanger → outro


    References mentioned in this part:

    • Mojo Vision — smart contact lens company
    • Super absorbent polymer / sodium polyacrylate (SAP)
    • Stayfree, Whisper/Always — pad brands referenced


    Guest & product links:

    • Website: papayapads.com
    • Instagram: @papaya.india and @shagun.maheshwari
    • LinkedIn (Shagun): https://www.linkedin.com/in/maheshwarishagun/
    • LinkedIn (company): https://www.linkedin.com/company/papayaindia/

    Insta/TikTok: @BiohackingEve
    Website: www.BiohackingEve.com

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    30 mins
  • #20 Pt3: Could Endometriosis Be a Microbiome Disease?
    Jun 23 2026

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    In Part 3, Ronny Szelinsky moves into the frontier: AI-based endometrial diagnostics, the seeding event that shapes your baby's immune system at birth, the emerging theory that endometriosis may be a microbiome disease, and a clinical prediction for where gynaecological medicine is heading over the next decade. The episode closes with the curveball section, including book recommendations and perspectives on the gender health gap.

    Key Topics
    Seeding: how the birth canal colonises the newborn with foundational bacteria, and what C-section babies miss
    How to manually replicate seeding — and why most hospitals don't
    Why each successive birth reduces the mother's microbiome diversity
    AI diagnostics: inferring endometrial microbiome state from a vaginal swab (no biopsy)
    Applications for fertility clinics; pre-IVF screening; personalised probiotic protocols
    What is scientifically established vs currently speculative in the gynecological microbiome field
    Endometriosis as a potential endpoint of chronic microbiome dysfunction: the emerging theory
    Antimicrobial resistance and gynecological probiotics
    Why antibiotics sometimes trigger irregular bleeding — and the microbiome explanation
    Clinical prediction: microbiome assessment as routine gynaecological practice within ten years
    Curveball: recommended books, electrolytes, Rwanda project, ideal sidekick

    Timestamps
    [Part 3 start] — Seeding: the birth canal microbiome transfer
    [~05:00 into part] — C-section, missed seeding, manual replication
    [~08:00] — Why microbiome diversity declines with each birth
    [~10:00] — AI diagnostics: vaginal swab inference for endometrial state
    [~16:00] — Fertility clinic use cases; personalised probiotic prescribing
    [~20:00] — What is established vs speculative in the field
    [~23:00] — Endometriosis and the microbiome theory
    [~27:00] — Antibiotics, irregular bleeding, antimicrobial resistance
    [~30:00] — Ten-year clinical prediction
    [~33:00] — Curveball questions

    References and Resources
    Get Happy website: www.get-happy.com
    Ronny Szelinsky — LinkedIn: https://www.linkedin.com/in/ronny-szelinsky
    Darm mit Charme by Jill Enders (English: Gut — The Inside Story of Our Body’s Most Underrated Organ)
    Herzenssache by Prof. Michael Becker (not available in English) — book on the female heart and gender differences in cardiovascular medicine
    Boundless by Ben Greenfield — longevity and biohacking reference book; both Ronny and Judith recommend.


    Insta/TikTok: @BiohackingEve
    Website: www.BiohackingEve.com

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    43 mins
  • #20 Pt2: How the Pill Disrupts the Microbiome Long-Term
    Jun 9 2026

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    In Part 2, Ronny Szelinsky explains the mechanism behind oestrogen-driven microbiome collapse at menopause — and what can be done about it. He introduces the estrobolome, details the research behind Get Happy's Happy Fem probiotic formula, and explains why oral probiotics colonise the gynecological tract as effectively as vaginal delivery. This is the translational bridge between the science of Part 1 and the practical interventions of Part 3.



    Key Topics

    • How oestrogen controls the thickness of the vaginal and endometrial tissue, and what happens when it drops
    • Why UTIs become suddenly frequent after menopause — the biological mechanism
    • Vaginal dryness and pain during sex: the mucosal layer explained
    • The estrobolome: the bacterial community around the ovaries and its proposed role in oestrogen production
    • The contraceptive pill and its long-term impact on microbiome colonisation after stopping
    • Happy Fem: how the product was developed, the research methodology, and the fertility clinic partnerships
    • Why oral probiotics achieve equivalent vaginal colonisation to vaginal administration — three pathways
    • Lactobacillus CA-15: what the published research shows
    • Who should take vaginal probiotics and under what circumstances
    • When to pause: during pregnancy, and why
    • Dosing: six-month courses for specific goals; ongoing daily use for post-menopausal women



    Timestamps

    • [Part 2 start] — Hormone-microbiome axis, oestrogen and tissue thickness
    • [~05:00 into part] — Why UTIs spike at menopause
    • [~10:00] — The estrobolome: ovarian bacteria and oestrogen production
    • [~17:00] — Happy Fem: product development and research methodology
    • [~22:00] — Oral vs vaginal administration — clinical study results
    • [~27:00] — Lactobacillus CA-15: what it does
    • [~30:00] — Who should take it; when to pause; dosing logic



    References and Resources

    • Happy Fem product: www.get-happy.com
    • Lactobacillus CA-15

    Insta/TikTok: @BiohackingEve
    Website: www.BiohackingEve.com

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    36 mins