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Cardiology Today

Cardiology Today

Written by: Deconstructed Cardiology
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 Stay current with cardiovascular medicine without the time commitment. Every morning, we deliver concise audio summaries of the latest original research from top cardiology journals. Top 5 breakthrough studies briefed in under 5 minutes (perfect for your commute or between patients). PubMed links included for full articles. Perfect for cardiologists, cardiothoracic surgeons, cardiac nurses, researchers, and healthcare workers who need to stay informed but lack time to scan multiple journals daily. For educational and reference purposes only. Not intended as medical advice.© 2025 Deconstructed Cardiology LLC Hygiene & Healthy Living Science
Episodes
  • Name Bias Delays STEMI Diagnosis 02/24/26

    Name Bias Delays STEMI Diagnosis 02/24/26
    Feb 24 2026
    Welcome to Cardiology Today – Recorded February 24, 2026. This episode summarizes 5 key cardiology studies on topics like Healthcare disparities and Heart failure. Key takeaway: Name Bias Delays STEMI Diagnosis. Article Links: Article 1: Benefit of early initiation of disease-modifying therapy in community-based patients with suspected heart failure. (European heart journal) Article 2: Aortic Insufficiency Progression in Patients with Left Ventricular Assist Devices and Prior Impella Support. (The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation) Article 3: Longitudinal Trends and Contemporary Outcomes of Combined Heart-Lung Transplantation. (The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation) Article 4: Identification of a Highly Functional Effector CD8+ T Cell Program after Transplantation in Mice and Humans. (American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons) Article 5: Impact of name-based implicit bias on time to diagnosis and outcomes in ST-elevation myocardial infarction. (Heart (British Cardiac Society)) Full episode page: https://podcast.explainheart.com/podcast/name-bias-delays-stemi-diagnosis-02-24-26/ Featured Articles Article 1: Benefit of early initiation of disease-modifying therapy in community-based patients with suspected heart failure. Journal: European heart journal PubMed Link: https://pubmed.ncbi.nlm.nih.gov/40879671 Summary: The study concluded that initiating heart failure therapies when an elevated N-terminal pro-B-type natriuretic peptide level is detected in community-based patients with suspected heart failure may reduce the risk of early adverse outcomes. The analysis suggested a potential benefit from the early initiation of a sodium-glucose cotransporter two inhibitor and/or a mineralocorticoid receptor antagonist in these patients. This therapeutic approach applies to individuals with suspected heart failure who also have pre-existing non-heart failure related indications. The findings underscore the importance of prompt pharmacological intervention in managing early stages of heart failure. Article 2: Aortic Insufficiency Progression in Patients with Left Ventricular Assist Devices and Prior Impella Support. Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation PubMed Link: https://pubmed.ncbi.nlm.nih.gov/41730484 Summary: The study addressed a critical clinical concern regarding the incidence and risk factors for aortic insufficiency in patients receiving mechanical circulatory support. It focused on individuals who received Impella percutaneous temporary left ventricular assist devices, those with Impella followed by durable left ventricular assist devices, and those with durable left ventricular assist devices alone. Understanding aortic insufficiency progression is crucial for managing patients supported by these devices, as its incidence and specific risk factors have remained unclear in this population. This research highlighted the need for clarity regarding distinct clinical pathways and outcomes in these complex patient groups. Article 3: Longitudinal Trends and Contemporary Outcomes of Combined Heart-Lung Transplantation. Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation PubMed Link: https://pubmed.ncbi.nlm.nih.gov/41730483 Summary: The study found that combined heart-lung transplants in the United States experienced a gradual decline, but then showed a significant rise in procedures since 2014, particularly among adults. This shift represents an important change in the landscape of thoracic organ transplantation. Understanding these evolving longitudinal trends is critical for clinicians managing patients awaiting or undergoing this complex procedure. The research provides key insights into the contemporary patterns of combined heart-lung transplantation. Article 4: Identification of a Highly Functional Effector CD8+ T Cell Program after Transplantation in Mice and Humans. Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons PubMed Link: https://pubmed.ncbi.nlm.nih.gov/41730451 Summary: The study identified a highly functional effector C.D.8 positive T cell program crucial for post-transplantation immune responses in both mice and humans. Researchers found that agonism of the C.D.43 1B11 receptor in vitro induced C.D.8 positive T cell proliferation even with sub-threshold antigen stimulation. In vivo, C.D.43 1B11 agonism successfully overcame costimulation-blockade induced tolerance and significantly enhanced C.D.8 positive T cell cytokine ...
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  • Diabetes Ups Myocarditis Heart Failure Risk 02/23/26

    Diabetes Ups Myocarditis Heart Failure Risk 02/23/26
    Feb 23 2026
    Welcome to Cardiology Today – Recorded February 23, 2026. This episode summarizes 5 key cardiology studies on topics like antiplatelet therapy and longitudinal study. Key takeaway: Diabetes Ups Myocarditis Heart Failure Risk. Article Links: Article 1: Elevated Activin-A serum levels in patients with acute peripartum cardiomyopathy and during left ventricular recovery. (ESC heart failure) Article 2: Diabetes Increases the Risk of Heart Failure in Myocarditis: A Propensity-Matched Nationwide Database Analysis. (ESC heart failure) Article 3: Nomogram Model for Predicting 90-Day Excellent Outcome in Patients With Acute Vertebrobasilar Artery Occlusion Undergoing Endovascular Thrombectomy. (Journal of the American Heart Association) Article 4: Insomnia and Incident Cardiovascular Disease in US Hispanic/Latino Adults: Results From HCHS/SOL. (Journal of the American Heart Association) Article 5: Safety and Efficacy of Early Aspirin Administration After Intravenous Thrombolysis for Acute Ischemic Stroke (TREND-IVT): Rationale and Design of a Multicenter, Randomized, Placebo-Controlled Clinical Trial. (Journal of the American Heart Association) Full episode page: https://podcast.explainheart.com/podcast/diabetes-ups-myocarditis-heart-failure-risk-02-23-26/ Featured Articles Article 1: Elevated Activin-A serum levels in patients with acute peripartum cardiomyopathy and during left ventricular recovery. Journal: ESC heart failure PubMed Link: https://pubmed.ncbi.nlm.nih.gov/41728898 Summary: This study analyzed Activin-A serum levels in patients from the German Peripartum Cardiomyopathy registry both at acute diagnosis and during Left Ventricular recovery. It found that elevated circulating levels of Activin-A, a senescence-associated secretory phenotype factor, correlated with heart failure severity in acute Peripartum Cardiomyopathy patients at baseline. The investigation detailed the trajectory of Activin-A serum levels throughout the course of Left Ventricular functional recovery. This analysis highlights Activin-A as a potential biomarker relevant to the pathophysiology and recovery assessment in Peripartum Cardiomyopathy. Article 2: Diabetes Increases the Risk of Heart Failure in Myocarditis: A Propensity-Matched Nationwide Database Analysis. Journal: ESC heart failure PubMed Link: https://pubmed.ncbi.nlm.nih.gov/41728893 Summary: This propensity-matched nationwide database analysis found that diabetes significantly increased the risk of heart failure in patients hospitalized for myocarditis. The study reported that diabetes impacted both in-hospital and long-term outcomes in this patient group. Patients discharged alive were followed for a calendar year, demonstrating the sustained effect of diabetes on subsequent cardiac events. This analysis establishes diabetes as a critical comorbidity that exacerbates adverse outcomes in myocarditis. Article 3: Nomogram Model for Predicting 90-Day Excellent Outcome in Patients With Acute Vertebrobasilar Artery Occlusion Undergoing Endovascular Thrombectomy. Journal: Journal of the American Heart Association PubMed Link: https://pubmed.ncbi.nlm.nih.gov/41717945 Summary: This study developed and externally validated a nomogram model designed to predict 90-day excellent functional outcomes in patients with acute vertebrobasilar artery occlusion. The nomogram provides a crucial tool for patient selection in endovascular thrombectomy, a procedure proven effective for this condition which typically has mortality rates up to 80 percent. The model offers enhanced precision in identifying patients most likely to achieve a modified Rankin Scale score of 0-1 at 90 days. This predictive model addresses the significant challenge of patient selection in managing acute vertebrobasilar artery occlusion. Article 4: Insomnia and Incident Cardiovascular Disease in US Hispanic/Latino Adults: Results From HCHS/SOL. Journal: Journal of the American Heart Association PubMed Link: https://pubmed.ncbi.nlm.nih.gov/41717941 Summary: This study analyzed data from 3635 Hispanic/Latino adults and found a significant association between insomnia and incident cardiovascular disease. Insomnia was assessed using the Women’s Health Initiative Insomnia Rating Scale, evaluating group status, symptom severity, specific symptom dimensions, and sleep duration at baseline. The results demonstrated that insomnia is an independent cardiovascular risk factor in this specific demographic. This highlights the importance of screening for and managing insomnia to potentially mitigate cardiovascular risk in Hispanic/Latino populations. Article 5: Safety and Efficacy of Early Aspirin Administration After Intravenous Thrombolysis for Acute Ischemic Stroke (TREND-IVT): Rationale and Design of a Multicenter, Randomized, Placebo-Controlled Clinical Trial. Journal: Journal of the American Heart Association PubMed Link: https://pubmed.ncbi.nlm.nih.gov/41717940 Summary: The TREND-IVT trial is a multicenter, randomized,...
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  • AI Links Dental Care to Higher Heart Risk 02/23/26

    AI Links Dental Care to Higher Heart Risk 02/23/26
    Feb 23 2026
    Welcome to Cardiology Today – Recorded February 23, 2026. This episode summarizes 5 key cardiology studies on topics like electrocardiography and adverse outcomes. Key takeaway: AI Links Dental Care to Higher Heart Risk. Article Links: Article 1: Interferon-γ-Responsive Microglia-Derived Extracellular Vesicles Inhibited Neurogenesis After Stroke via MicroRNA-199a-5p/SIRT1 Axis. (Journal of the American Heart Association) Article 2: Annual Trends in Risk Factor Control Status at the Time of Ischemic Stroke in South Korea. (Journal of the American Heart Association) Article 3: Short-Term Exposure to Ambient Ozone and Fine Particulate Matter and Its Components Increases the Risk of In-Hospital Adverse Outcomes in Patients With Acute Myocardial Infarction: A Time-Stratified Case-Crossover Study. (Journal of the American Heart Association) Article 4: Cold Waves and Elevation Strengthen the Association of Particulate Matter Exposure With Hypertension Prevalence: A Large Multiregional Study in China. (Journal of the American Heart Association) Article 5: Inadequate Preventive Dental Care Is Associated With Higher Cardiovascular Risk Identified by ECG-Based Artificial Intelligence Algorithms. (Journal of the American Heart Association) Full episode page: https://podcast.explainheart.com/podcast/ai-links-dental-care-to-higher-heart-risk-02-23-26/ Featured Articles Article 1: Interferon-γ-Responsive Microglia-Derived Extracellular Vesicles Inhibited Neurogenesis After Stroke via MicroRNA-199a-5p/SIRT1 Axis. Journal: Journal of the American Heart Association PubMed Link: https://pubmed.ncbi.nlm.nih.gov/41717953 Summary: This study found that interferon-gamma-responsive microglia-derived extracellular vesicles inhibited neurogenesis after stroke. This inhibition occurred via the microRNA-199a-5p/SIRT1 axis, revealing a specific molecular mechanism. The data demonstrated a pathway contributing to impaired neurological function recovery following cerebral ischemia. This new understanding identifies a potential therapeutic target to enhance neurogenesis and improve patient outcomes after stroke. Article 2: Annual Trends in Risk Factor Control Status at the Time of Ischemic Stroke in South Korea. Journal: Journal of the American Heart Association PubMed Link: https://pubmed.ncbi.nlm.nih.gov/41717952 Summary: This study evaluated annual trends in the control of major risk factors at the time of ischemic stroke in South Korea from 2011 to 2022. Researchers analyzed data from a nationwide registry, focusing on hypertension, diabetes, and dyslipidemia. The findings from this real-world assessment identified specific areas where current prevention guidelines for ischemic stroke need greater clinical attention. This work helps improve early stroke outcomes by highlighting gaps in risk factor management. Article 3: Short-Term Exposure to Ambient Ozone and Fine Particulate Matter and Its Components Increases the Risk of In-Hospital Adverse Outcomes in Patients With Acute Myocardial Infarction: A Time-Stratified Case-Crossover Study. Journal: Journal of the American Heart Association PubMed Link: https://pubmed.ncbi.nlm.nih.gov/41717950 Summary: This study found that short-term exposure to ambient ozone and fine particulate matter with a diameter of less than or equal to 2.5 micrometers increased the risk of in-hospital adverse outcomes for patients with acute myocardial infarction. The time-stratified case-crossover study, conducted in Beijing, demonstrated this association between air pollutants and patient morbidity. This data highlights the critical impact of environmental factors on immediate post-infarction prognosis. Clinicians should consider air quality in managing acute myocardial infarction patients. Article 4: Cold Waves and Elevation Strengthen the Association of Particulate Matter Exposure With Hypertension Prevalence: A Large Multiregional Study in China. Journal: Journal of the American Heart Association PubMed Link: https://pubmed.ncbi.nlm.nih.gov/41717949 Summary: This large multiregional study in China found that cold waves and geographic elevation strengthened the association of particulate matter exposure with hypertension prevalence. Researchers analyzed data from 27000 adults, demonstrating that these co-occurring environmental stressors exacerbate the known risk of air pollution for hypertension. The data revealed significant interactive effects between long-term particulate matter exposure, cold weather, and altitude. This understanding is crucial for public health strategies addressing hypertension in varied geographical and climatic conditions. Article 5: Inadequate Preventive Dental Care Is Associated With Higher Cardiovascular Risk Identified by ECG-Based Artificial Intelligence Algorithms. Journal: Journal of the American Heart Association PubMed Link: https://pubmed.ncbi.nlm.nih.gov/41717947 Summary: This study found that inadequate preventive dental care was associated with a higher ...
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