• #221 Colon Cancer Screening After Age 75 | 5 Pearls Segment Part 3
    Oct 21 2026

    “Should you stop screening for colorectal cancer (CRC) at 75?”

    This episode explores how to individualize screening decisions based on life expectancy, prior colonoscopy findings, and procedural risks. Learn how to navigate these nuanced conversations, avoid age-based assumptions, and use strategies like mailed FIT kits and offering screening choices to help more patients get screened.


    🔹Sponsor: Search “Amazon Pharmacy Nationwide Home Delivery" in your EHR to get home delivery (often same-day). Learn more here!


    🔹Transcript and Show Notes

    01:18 | Screening >75 yo?

    10:06 | Takeaways on Colorectal Cancer Screening After 75

    10:37 | Systems thinking: How do we get to an 80% screening rate


    Tags: Core IM, Internal Medicine, Colorectal Cancer Screening, Gastroenterology, Cancer Screening



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    17 mins
  • #220 CRC Screening Nuances: 5 Pearls Segment Part 2
    Oct 8 2026

    “What’s the best way to screen?” This episode breaks down the pros, limitations, and follow-up needs of FIT, Cologuard, CT colonography, and colonoscopy to help you choose the right screening option for your patients. Also learn practical colonoscopy surveillance intervals based on polyp size, number, and pathology.


    🔹Sponsor: Search “Amazon Pharmacy Nationwide Home Delivery" in your EHR to get home delivery (often same-day). Learn more here!


    🔹Transcript and Show Notes

    01:24 | Screening Options Besides Colonoscopy

    11:22 | How FIT, FIT-DNA, and CT colonography differ and when each makes sense.

    12:52 | Colonoscopy and Frequency

    19:29 | How adenoma number, size, and histology guide surveillance intervals.


    Tags: Core IM, Internal Medicine, Colorectal Cancer Screening, Gastroenterology, Cancer Screening



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    21 mins
  • #219 Updates in Triglycerides
    Sep 29 2026

    “The triglycerides are high. Now what?” This episode breaks down a practical approach to elevated TGs, from knowing when to check ApoB or non-HDL-C to choosing lifestyle changes, lipid-lowering medications, and when to suspect an underlying genetic disorder.


    🔹Transcript and Show Notes

    02:17 | Check a non-HDL-C or ApoB if TGs are ≥150 mg/dL

    07:18 | Address waist circumference and lifestyle before meds for high TGs

    10:52 | Dr. Watson’s 3-day carbohydrate responsiveness trial

    17:07 | Order a fasting or nonfasting lipid panel?

    19:00 | When do you reach for TG-lowering medications?

    25:26 | Familial chylomicronemia syndrome (FCS)


    Tags: CoreIM, Medical Education, Hypertriglyceridemia, ACC AHA lipid guidelines, lipid guidelines 2026, cardiovascular risk



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    34 mins
  • #218 Early-Onset CRC: 5 Pearls Segment Part 1
    Sep 23 2026

    “Too young for colon cancer.” This episode unpacks the red flags of early-onset CRC, from blood in the stool and iron deficiency anemia to persistent abdominal pain and changes in bowel habits, and offers practical pearls for closing the clinical loop. Also learn why a “negative” family history may need a yearly refresh.


    🔹Sponsor: Search “Amazon Pharmacy Nationwide Home Delivery" in your EHR to get home delivery (often same-day). Learn more here!


    🔹Transcript and Show Notes


    01:45 | Colorectal cancer rising in younger adults

    06:42 | Why screening starts at age 45

    08:15 | What may be driving early-onset colorectal cancer

    13:37| Key takeaways: symptoms, follow-up, and family history


    Tags: Colorectal Cancer Screening, Internal Medicine, Gastroenterology, Cancer Screening, Oncology



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    15 mins
  • #217 Treatment for Alcohol Use Disorder: 5 Pearls Segment
    Sep 16 2026

    “It didn’t work.” This episode breaks down practical treatment options (dosing options for naltrexone, acamprosate, topiramate, gabapentin) and counseling pearls to help you meet patients where they are and support their recovery. Also discover blind spots in detox and rehab centers.

    🔹Transcript and Show Notes

    🔹 Explore ACP’s Substance Use Disorder Education Hub for videos and an AI-powered patient simulation to practice alcohol-use conversations: https://www.coreimpodcast.com/SUDhub

    Alcohol Use and Chronic Health Conditions Mini Video Series

    01:55 | #1: Naltrexone

    12:06 | #2 Acamprosate

    16:15 | #3: Topiramate

    21:12 | #4: Other meds

    29:31 | #5: Detox and rehab blind spots


    Tags: CoreIM, Medical Education, Addiction Medicine, Alcohol Withdrawal, Addiction Treatment, GLP-1, pharmacology



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    38 mins
  • #216 Clinician Grief: At the Beside Segment
    Sep 8 2026

    Have you ever lost a patient and found yourself thinking about them long after the shift ended? This episode explores the grief clinicians can carry after a patient dies, including the losses that aren’t always obvious. We also discuss ways to work through that grief, recognize when it becomes complicated, and lean on your team for support.


    🔹Transcript and Shownotes

    04:12 | What is Clinician Grief?

    10:02 | Types of Losses

    10:22 | Loss of a close relationship with a particular patient

    12:56 | Loss due to a professional's identification with the pain of family members

    13:56 | Loss of one's unmet goals and expectations and one's professional self-image and role

    18:47 | Loss related to one's personal system of beliefs and assumptions about life

    21:30 | Past unresolved losses or anticipated future losses

    23:29 | The death of the self

    25:44 | Coping


    Tags: CoreIM, Medical Education, Clinician Wellbeing, Burnout, Secondary Traumatic Stress, Complicated Grief, Coping With Grief, Medical humanities, medical ethics



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    40 mins
  • #215 Gallbladder & Biliary Testing: 5 Pearls Segment
    Aug 25 2026

    How to choose between RUQ ultrasound, CT, HIDA, MRCP, EUS, and ERCP based on the clinical picture? When should you move from diagnostic imaging to therapeutic ERCP, and what should you know about sphincterotomy, stents, and stone removal? Plus, how to interpret bile duct dilation without jumping straight to obstruction?


    🔹Sponsor: Oakstone CME

    Use the code "CORE25" for 25% off: https://www.coreimpodcast.com/MKSAP


    🔹Transcript and Shownotes


    02:11 | Pearl 1: Gallbladder Problems Spectrum

    07:33 | Pearl 2: Choose Imaging Strategically: Start with RUQUS, Escalate as Needed

    14:34 | Pearl 3: Biliary Tree Diagnostics

    19:19 | Pearl 4: Invasives that are Diagnostic and Therapeutic

    27:06 | Pearl 5: Stenting in ERCP


    Tags: CoreIM, Internal Medicine, Medical Education, Gallstones, Cholecystitis, Biliary Disease, ERCP, Biliary Imaging



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    35 mins
  • #214 Hyponatremia Management: A Core IM Classic
    Aug 12 2026

    Throwback: Should you really fluid-restrict every patient with SIADH? When can IV fluids make hyponatremia better or worse? Are salt tabs actually doing enough? And what can urine studies tell you before you start treatment? Join us for a practical, physiology-driven approach to hyponatremia management, from fluids and solutes to loop diuretics and identifying the underlying cause.


    🔹Sponsor: Search “Amazon Pharmacy Nationwide Home Delivery" in your EHR to get home delivery (often same-day). Learn more here.


    🔹Transcript and Shownotes


    6:46 | Pearl 1: Key Principles

    15:13 | Pearl 2: Fluids in hyponatremia

    26: 03 | Pearl 3: Solutes in hyponatremia management

    35:49 | Pearl 4: Lasix in hyponatremia management

    40:05 | Pearl 5: Etiologies


    Tags: CoreIM, Internal Medicine, Medical Education, SIADH, Fluid Restriction, Nephrology, Hospital Medicine, Urine Osmolality



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    45 mins