In this edition, we look at the impact of GLP-1s on total joint replacement, the safety of NSAID's and more.

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GLP-1s may have profound impact on total joint replacement

NSAID use may be safe prior to total joint arthroplasty

Complication risk may be lower for revision TJA when performed in ASC

Despite improved function, patients with elbow dislocation often report long-term pain

Osteochondral allograft transplant may treat pediatric elbow osteochondritis dissecans

References:

Acuña AJ, et al. Paper 33. Presented at: American Association of Hip and Knee Surgeons Annual Meeting; Oct. 23-26, 2025; Dallas.

Foran JRH, et al. Paper 31. Presented at: American Association of Hip and Knee Surgeons Annual Meeting; Oct. 23-26, 2025; Dallas.

Healio Interviews

Perkins CA, et al. Am J Sports Med. 2025;doi:10.1177/03635465251366903.

Plaisier N, et al. Paper 29. Presented at: Orthopaedic Trauma Association Annual Meeting; Oct. 15-18, 2025; Phoenix.

In this edition, immunotherapy in advanced lung cancer, updates in EGFR-mutated lung cancer and more.

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VIDEO: Immunotherapy in advanced lung cancer among highlights from ESMO 2025

VIDEO: Updates in EGFR-mutated lung cancer from ESMO 2025

VIDEO: DeLLphi-303 results show 'major jump in survival' for SCLC patients

Emphysema found during lung cancer screening raises risk for mortality

Q&A: More nonsmokers developing lung cancer due to radon exposure, air pollution

References

· González Gutiérrez J, et al. Radiology. 2025;doi:10.1148/radiol.250949.

· Healio Interviews

· Healio Interviews

· Healio Interviews

· Paulson KG, et al. Abstract OA13.01. Presented at IASLC World Conference on Lung Cancer; Sept. 6-9, 2025; Barcelona.

In this edition, we look at robotic-assisted surgery, dislocation risk in fixed-bearing THA and more.

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Higher head-to-cup ratio, robotic-assisted surgery may lower dislocation rate after THA

Fully maximizing bearing diameter may reduce dislocation risk in fixed-bearing THA

How may GLP-1s impact nutrition prior to orthopedic surgery?

Medicare contractors propose coverage restriction of peripheral nerve block procedures

Physician content on TikTok may guide patient education

References:

Expert submission

Healio Interviews

Healio Interviews

Kobayashi JK, et al. Paper 54. Presented at: American Association of Hip and Knee Surgeons Annual Meeting; Oct. 23-26, 2025; Dallas.

Wang E, et al. Maximizing bearing diameter markedly lowers dislocations in primary total hip arthroplasty. Presented at: American Association of Hip and Knee Surgeons Annual Meeting; Oct. 23-26, 2025; Dallas.

In this edition, FDA warns complications following radiofrequency microneedling device use, chronic hand eczema considered "common" disease, and more.

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Q&A: FDA warns of radiofrequency microneedling risks; here's what to know

Chronic hand eczema now considered a 'common' skin disease in US

'Unproven' topical estrogens for the face may bring some risks

FDA approves Restylane Lyft to treat receding chin

References

Chovatiya R, et al. Prevalence of self-reported physician diagnosis of chronic hand eczema in adults: A cross-sectional study of more than 10,000 participants in the general population – Results from the CHECK study in the United States. Presented at: Fall Clinical Dermatology Conference; Oct. 23-26, 2025; Las Vegas.

Farkas E, et al J Am Acad Dermatol. 2025;doi:10.1016/j.jaad.2025.08.050.

Healio Interviews

Press Release

In this edition, we look at rehabilitation protocols, how AI can help patients with total knee arthroplasty, synthetic THC and more.

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'Quiet knee' rehabilitation protocol may reduce opioid exposure after TKA

AI-enabled decision aid may improve TKA decision-making

Synthetic THC may not reduce opioid intake after TKA

Lorecivivint yields 'meaningful' improvements in knee osteoarthritis at 1 year

Corticosteroid injections yield 'disappointing' response in knee osteoarthritis

References:

Baker J. Abstract 2624. Presented at: ACR Convergence 2025; Oct 24-29, 2025; Chicago.

Bhatti P, et al. Poster 30. Presented at: American Association of Hip and Knee Surgeons Annual Meeting; Oct. 23-26, 2025; Dallas.

Jayakumar P, et al. Paper 30. Presented at: American Association of Hip and Knee Surgeons Annual Meeting; Oct. 23-26, 2025; Dallas.

Jennings JM, et al. Paper 10. Presented at: American Association of Hip and Knee Surgeons Annual Meeting; Oct. 23-26, 2025; Dallas.

Yazici Y. Abstract 2626. Presented at: ACR Convergence 2025; Oct 24-29, 2025; Chicago.

In this edition, Congress reintroduces the Safe Step Act, an expert expresses doubt about the benefits of TrumpRx and more.

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Congress reintroduces Safe Step Act to amend step therapy policies

Q&A: TrumpRx, Pfizer deal sidestep health insurance companies

Complete hair regrowth for some with alopecia after 3-year ritlecitinib treatment

Waterproof bandages 'reasonable alternative' to petroleum-based wound care

References

· Bell MC, et al JAMA Dermatol. 2026;doi:10.1001/jamadermatol.2025.4051.

· Healio Interviews

· King B, et al. Abstract #LBA-335. Presented at: European Academy of Dermatology and Venereology Congress; Sept. 17-20, 2025; Paris.

In this edition, increased lung cancer screening improving outcomes, overall survival data from FLAURA2 trial and more.

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Increased lung cancer screening improving outcomes, but rates 'still too low'

VIDEO: Overall survival data from FLAURA2 trial presented at WCLC

Updated NCCN guidelines on NSCLC put spotlight on biomarker testing

'Never too late': Smoking cessation after cancer diagnosis can extend survival

New treatments worsened income-based survival disparities for lung cancer, melanoma


References

· American Lung Association 2025 State of Lung Cancer.

· Khor S, et al. JCO Oncol Adv. 2025;doi:10.1200/OA-25-00026.

· National Comprehensive Cancer Network.

· Planchard D, et al. Abstract PL02.06. Presented at IASLC World Conference on Lung Cancer; Sept. 6-9, 2025; Barcelona.

· Tohmasi S, et al. J Natl Compr Canc Netw. 2025;doi:10.6004/jnccn.2025.7059.

In this edition, we look at the first FDA approval of an oral therapy for chronic spontaneous urticaria, and more.

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FDA approves first oral therapy for chronic spontaneous urticaria

Denifanstat safe, effective in acne vulgaris treatment

FDA approves Zoryve cream 0.05% for pediatric atopic dermatitis

The 'Zoom boom' effect: Post-pandemic cost concerns for facial cosmetic procedures

References:

F Xiang, et al. Abstract #LBA-213. Presented at: European Academy of Dermatology and Venereology Congress; Sept. 17-20, 2025; Paris.

Pecora V, et al. J Drugs Dermatol. 2025;doi:10.36849/JDD.9102.

Press Release

Press Release