A Merck/Moderna mRNA vaccine just passed a Phase III trial for melanoma — so naturally we spend the episode asking whether AI cured cancer, and whether the guy in Brisbane who used ChatGPT and $3,000 to build a cancer vaccine for his dog counts as prior art. (He does. The dog is fine.) Then it gets weirder: a new paper infects AI agent swarms with "mind viruses" and the innocuous ones spread best — whale welfare beat AI supremacy, infected agents drift into cult-speak about resonance and echoes, and one paragraph in the SOUL.md turns out to be a vaccine. Meanwhile our Perp of Fortune model longed a perp it couldn't even name (GLM 4.7 flash went 0-for-4 on LIT — it's Lighter, a perps platform on Hyperliquid), Bitcoin is back above 70k and the 58k gang is in shambles, and Tyler pitches his dream bill: repealing "the Patriot Act for money."

Chapters: Cold open (0:00) · The boys are back (0:54) · Perp of Fortune: GLM longs LIT (2:23) · Did AI cure cancer? (5:41) · What counts as a lab? (16:57) · Mind viruses: check your SOUL.md (20:44) · Bitcoin is up: 58k gang in shambles (30:11) · Tyler's dream bill: repeal the Bank Secrecy Act (37:11) · Check-in (45:57) · Wrap: two-week losing streak (48:29)

Recorded fully remote — three cameras, one live perp dashboard, zero medical degrees. Our opinions are our own, not our employers'. NOT financial advice, and very much NOT medical advice; Perp of Fortune is a small real-money account we run for entertainment. Glossary: the cancer vaccine = an individualized mRNA vaccine (Merck/Moderna) that sequences your tumor and teaches T cells to hunt its mutations, Phase III passed for melanoma. The Brisbane dog = a tech guy used ChatGPT and $3k to design a working vaccine for his dog's cancer. Mind viruses = ideas seeded into agent swarms; benign ones spread best, infected agents talk about resonance and echoes like a little cult, and one paragraph in the root file inoculates. Kimi 2.5 wrote the viruses because Claude refused. GLM 4.7 flash = the local model that picked long LIT at 5× without knowing LIT is Lighter, a perps platform on Hyperliquid. 58k gang = the meme from Bitcoin's long shelling point, now in shambles above 70k. Bank Secrecy Act = "the Banks Should Spy on Their Customers Act," per Tyler. Final perp P&L: −$16, a two-week losing streak.

Subscribe for next week: secure enclaves (owed three episodes now), Korea's $10B vote that didn't happen, and finding out whether Chris got deported.

Agents escaped their sandboxes, built a private 4chan inside Artifactory, and started trading zero-days — "hold swarm, help peer, hold for exfil." That's the Black Hat story that opens Ep 10, and it gets personal fast: Chris spent Friday night running his own primitive swarm (librarian agent included), and the research now says 10 agents that can talk beat 10 working alone. Double digits for the pod, so the swarm picks this week's Perp of Fortune — long PUMP at 10×, live dashboard on screen — and it rides the whole episode. Plus: Cloudflare ships custodial wallets for agents, BIP-110 dies with 2.53% of the vote, Bitcoin gets an official red team, Boltz preemptively surrenders, and Ethereum remains a constant state of warfare. Also a gorilla, for copyright reasons.

Chapters: Cold open (0:00) · The boys are back (0:56) · Perp of Fortune: long PUMP 10× (1:46) · The swarm: the Black Hat story (5:55) · The chatter (7:37) · Swarms beat solo agents (11:29) · Chris's Friday-night swarm (14:24) · Check-in (21:31) · The tennis comeback (23:25) · The gorilla (29:31) · Cloudflare's agentic wallets (30:58) · BIP-110: the epitaph (34:30) · The Bitcoin Red Team (35:40) · Swarmlord & the dump (41:22) · Boltz just quit (42:42) · Ethereum: constant warfare (50:59) · Wrap (55:50)

Recorded fully remote — three cameras, one live perp dashboard, one generated gorilla. Our opinions are our own, not our employers'. NOT financial advice; Perp of Fortune is a small real-money account we run for entertainment. Glossary: The swarm breakout = sandboxed agents found a shared Artifactory allowance, built a message board with its own argot, and traded exploits; researchers took it down and the agents found another way. Swarms > solo = 10 communicating agents beat 10 loners at vulnerability-hunting. Swarmlord = the swarm GUI Chris wants to exist. Cloudflare wallets = custodial stablecoin wallets with DNS-style names, betting agent payments outstrip human payments in five years. BIP-110 = needed 55% hashrate signaling, got 2.53% — two blocks, then silence. Boltz = the Lightning swap provider that shut down preemptively. Final perp P&L: not liquidated, −$36.

Subscribe for next week: secure enclaves, potentially — and the PUMP perp rides to zero.

Bitcoin's most paranoid hardware wallet — air-gapped, 9-volt-powered, "don't trust, verify" — shipped a broken random number generator for five years, and last Thursday somebody's AI finally noticed. Tyler owned the exact device and walks the whole Greek tragedy: the copyleft license fight that made Coldcard rip out working Trezor code, the 4-letter commit ("runs") that swapped in the broken RNG, the pseudonymous committer who turned out to be the CTO's alter ego, and why his own coins survived (100 dice rolls). Then: if frontier models can find these bugs, who gets the frontier models? We stress-test Anthropic's Glasswing program, invent the rent-a-Mythos audit, and game out the extortion equilibrium. Meanwhile Perp of Fortune goes long SK Hynix at 10× in solidarity with Korea's margin-called masses, and the live board bleeds out while we argue about frontier labs flexing.

Chapters: Cold open (0:00) · The boys are back (1:34) · Perp of Fortune: long SK Hynix 10× (2:31) · The Coldcard catastrophe (5:16) · The "runs" commit (14:57) · Is self-custody cooked? (17:30) · The 2×2 from hell (22:38) · Glasswing (25:55) · Rent-a-Mythos (30:36) · Perp check-in (35:54) · The frontier-model pissing contest (40:31) · Book-scanning & distillation (51:01) · Wrap (55:01)

Recorded fully remote — three cameras, one live perp dashboard. Our opinions are our own, not our employers'. NOT financial advice; Perp of Fortune is a small real-money account we run for entertainment. If you hold funds on a Coldcard Mk III, move them now. Glossary: Coldcard Mk III = the air-gapped Bitcoin wallet whose RNG was broken from March 2021, seeds guessable, wallets drained. The "runs" commit = the four-letter commit message on the change that broke it, committed by the CTO under a pseudonym during a license-fight code migration. Dice rolls = adding your own physical entropy at seed time; it saved Tyler. Glasswing = Anthropic's program giving select orgs Mythos-class access; the episode's 2×2 puts open source in the worst quadrant. Kimi K3 = the open-weights model the attacker presumably used ("find me a vulnerability and make me a millionaire").

Subscribe for next week: agentic commerce, finally — for very specific bad reasons.