• Is Lower LDL Actually Better? New Research Has an Answer
    May 4 2026

    Is lower LDL cholesterol actually better for your heart? In this video, I break down the brand-new results from the EZ-Pave study to answer the question that keeps my patients up at night: How low should your cholesterol really go?

    As a vascular surgeon, I see the end-stage results of heart disease every day.

    We’ve heard the "lower is better" mantra for decades, but new research is finally providing the hard evidence we need to settle the debate.

    Study link: https://www.nejm.org/doi/full/10.1056/NEJMoa2600283

    We’re looking at how LDL cholesterol levels impact actual cardiovascular events and whether adding medications like ezetimibe truly changes the outcome for your heart health.

    If you’ve been skeptical about statins or confused by conflicting health trends, this breakdown of the latest science is for you. My mission is to put myself out of business by giving you the truth about prevention before you ever need to see me in the operating room.

    For educational purposes only. Not medical advice. Always consult your healthcare provider before changing any treatment plan.

    Sign up for more information on my own practice here: https://corsighthealth.com/

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    ___________________________
    🧬 About Dr. Lily Johnston

    Dr. Johnston is a double board-certified vascular and general surgeon in San Diego, specializing in metabolic and cardiovascular prevention. She’s the founder of CorSight Health and a passionate advocate for reimagining how medicine approaches chronic disease.

    #MetabolicHealth #CardiovascularPrevention #HeartHealth #Longevity #InsulinResistance #DrLilyJohnston #DrLily #WomenInMedicine #Surgeon #VascularSurgeon #PreventiveMedicine #PADPrevention #HeartAttackRisks #HealthPortfolio #California #SanDiego #Arizona #Virginia #Minnesota

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    24 mins
  • The Truth About Aspirin and Heart Attack Prevention
    Apr 27 2026

    I've seen daily aspirin save lives from heart attack — and cause fatal bleeds. As a vascular surgeon, here's my honest take on heart health.

    The answer isn't yes or no — it depends entirely on who you are.

    In this video I break down the three groups you need to know:

    ✅ Who SHOULD take daily aspirin — if you've already had a heart attack, stroke, or stent, aspirin for secondary prevention of heart disease is still one of the most evidence-backed interventions we have.

    ❌ Who SHOULD NOT — the 2022 USPSTF guidelines quietly changed the recommendations for primary prevention. If you haven't had a cardiovascular event, daily aspirin may be doing more harm than good.

    ⚠️ The gray zone — two situations where the answer gets complicated: elevated coronary artery calcium (CAC) scores and high Lp(a) (lipoprotein a). Both raise your cardiovascular risk in ways the standard guidelines don't fully account for.

    This is the conversation your doctor should be having with you — but often doesn't have time for.

    I'm a vascular surgeon teaching the prevention side of medicine — the part most doctors don't have time to cover. Subscribe for more evidence-based answers on heart disease, metabolic health, and longevity.

    Sign up for more information on my own practice here: https://corsighthealth.com/

    High Quality 3rd-party tested supplements at Fullscript (10% discount): https://us.fullscript.com/welcome/ljohnstonmd/store-start

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    ___________________________
    🧬 About Dr. Lily Johnston

    Dr. Johnston is a double board-certified vascular and general surgeon in San Diego, specializing in metabolic and cardiovascular prevention. She’s the founder of CorSight Health and a passionate advocate for reimagining how medicine approaches chronic disease.

    #MetabolicHealth #CardiovascularPrevention #HeartHealth #Longevity #InsulinResistance #DrLilyJohnston #DrLily #WomenInMedicine #Surgeon #VascularSurgeon #PreventiveMedicine #PADPrevention #HeartAttackRisks #HealthPortfolio #California #SanDiego #Arizona #Virginia #Minnesota

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    24 mins
  • Ask Me (Almost) Anything With Dr Johnston | Live Q&A
    Apr 20 2026

    We hit all the high points today! Nutrition, exercise, lipids, dental health, hormones, and more. We had amazing participation and it was wonderful to have a chance to interact with everyone in real time. Thanks SO much for taking some of your precious weekend to talk cardiovascular health, heart scans, CAC scores, and all the other nerdy prevention things with me. Hope you enjoyed it! If you want me to do more of these in the future, please say so in the comments!

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    ___________________________
    🧬 About Dr. Lily Johnston

    Dr. Johnston is a double board-certified vascular and general surgeon in San Diego, specializing in metabolic and cardiovascular prevention. She’s the founder of CorSight Health and a passionate advocate for reimagining how medicine approaches chronic disease.

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    1 hr and 43 mins
  • Can You Unclog Arteries? A Vascular Surgeon Reacts to Dr Kevin Ham ​
    Apr 13 2026

    Plaque reversal is one of the most debated topics in preventive cardiology, so in this video I react to Dr. Kevin Ham’s CAST protocol for plaque reversal: Causes, Adding Cures, Strengthening the Body, and Training the Mind and Body.

    Overall, I think this is a thoughtful framework and I agree with much of it. But as a vascular surgeon who treats advanced atherosclerosis, I also add some nuance around what “plaque reversal” really means, what may be missing from this conversation, and where I’d want more granularity in a real-world cardiovascular prevention plan.

    We talk about the causes of plaque buildup, metabolic health, lifestyle change, cardiovascular risk reduction, and the difference between improving risk factors versus actually changing plaque biology. I also share where I think protocols like this can be helpful—and where they risk oversimplifying atherosclerosis.

    If you’re trying to understand plaque reversal, atherosclerosis, heart disease prevention, metabolic health, LDL, ApoB, inflammation, insulin resistance, and cardiovascular risk, this video will help you think more clearly about the problem.

    Let me know in the comments: Do you think “plaque reversal” is a useful term, or does it create more confusion than clarity?

    #PlaqueReversal #Atherosclerosis #HeartDisease #CardiovascularHealth #MetabolicHealth #Prevention

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    ___________________________
    🧬 About Dr. Lily Johnston

    Dr. Johnston is a double board-certified vascular and general surgeon in San Diego, specializing in metabolic and cardiovascular prevention. She’s the founder of CorSight Health and a passionate advocate for reimagining how medicine approaches chronic disease.

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    21 mins
  • I'm a Vascular Surgeon — Stop Getting Repeat CAC Scans. Here's Why
    Apr 13 2026

    If you’ve had a positive calcium score (CAC score), you’ve probably asked the obvious next question: when should I repeat it?

    In this video, I explain why I generally do not order another calcium score if the first one is positive—and what I prefer to use instead to follow atherosclerosis over time.

    We walk through what a coronary artery calcium score actually measures, why it’s really just the tip of the iceberg, and why a higher repeat score does not necessarily mean your treatment failed. I also explain the difference between calcified plaque and soft, lipid-rich plaque, why that distinction matters for heart attack and stroke risk, and why serial CAC testing often adds less useful information than people think.

    I also cover:
    • why calcium scores can be helpful as a one-time risk assessment tool
    • why I’m more cautious about relying on CAC in younger patients
    • when I will repeat a calcium score
    • why I prefer more informative tools like CCTA and CIMT for tracking disease over time

    If you’re trying to understand calcium score progression, plaque stabilization, soft plaque, coronary artery disease, heart disease prevention, stroke prevention, ApoB, Lp(a), statins, and cardiovascular risk, this video is for you.

    Let me know in the comments: If your first calcium score was positive, would you want to repeat it—or would you rather use a different test to follow your risk?

    #CalciumScore #CACScore #HeartDiseasePrevention #Atherosclerosis #CardiovascularHealth #CIMT #CCTA

    Sign up for more information on my own practice here: https://corsighthealth.com/

    High Quality 3rd-party tested supplements at Fullscript (10% discount): https://us.fullscript.com/welcome/ljohnstonmd/store-start

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    ___________________________
    🧬 About Dr. Lily Johnston

    Dr. Johnston is a double board-certified vascular and general surgeon in San Diego, specializing in metabolic and cardiovascular prevention. She’s the founder of CorSight Health and a passionate advocate for reimagining how medicine approaches chronic disease.

    #MetabolicHealth #CardiovascularPrevention #HeartHealth #Longevity #InsulinResistance #DrLilyJohnston #DrLily #WomenInMedicine #Surgeon #VascularSurgeon #PreventiveMedicine #PADPrevention #HeartAttackRisks #HealthPortfolio #California #SanDiego #Arizona #Virginia #Minnesota

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    10 mins
  • Is Your Candle Slowly Poisoning You? Vascular Surgeon Reacts to Joe Rogan
    Apr 13 2026

    Joe Rogan got half a million people talking about what's happening inside their blood vessels. As a vascular surgeon, I've spent my career trying to do exactly that. So when a celebrity does it for me, I pay attention (and thank my lucky stars ;).

    In the clip, Dr. Shauna Swan joins Joe Rogan to discuss the surprising hazards linked to everyday household products. In my reaction, I go through the actual studies behind the microplastics- and forever chemicals-cardiovascular disease conversation: what the data show, where the evidence is genuinely alarming, and where the certainty online is running about three years ahead of the science. Because both things are true.

    What we cover:
    — Microplastics found inside arterial plaques — and what that study actually says
    — PFAS (forever chemicals), phthalates, and other endocrine disruptors
    — Why association isn't causation and why that matters for your next doctor's appointment
    — What to actually do with genuine scientific uncertainty

    The signal is real. The panic is premature. You deserve to know the difference.

    If this video has you wondering whether you already have plaque — that's exactly the right question. Here's where to go next: https://youtu.be/-lt_2swYFhY?si=bRiZyDVY5QAxVvu8

    📚 Studies referenced:
    1. Marfella R, Prattichizzo F, Sardu C, Fulgenzi G, Graciotti L, Spadoni T, et al. Microplastics and Nanoplastics in Atheromas and Cardiovascular Events. N Engl J Med. 2024;390(10):900–10. doi:10.1056/nejmoa2309822
    2. Dunder L, Salihovic S, Varotsis G, Lind PM, Elmståhl S, Lind L. Plasma levels of per- and polyfluoroalkyl substances (PFAS) and cardiovascular disease - Results from two independent population-based cohorts and a meta-analysis. Environ Int. 2023 Nov;181:108250. doi: 10.1016/j.envint.2023.108250. PMID: 37832261.

    Sign up for more information on my own practice here: https://corsighthealth.com/

    High Quality 3rd-party tested supplements at Fullscript (10% discount): https://us.fullscript.com/welcome/ljohnstonmd/store-start

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    ___________________________
    🧬 About Dr. Lily Johnston

    Dr. Johnston is a double board-certified vascular and general surgeon in San Diego, specializing in metabolic and cardiovascular prevention. She’s the founder of CorSight Health and a passionate advocate for reimagining how medicine approaches chronic disease.

    #MetabolicHealth #CardiovascularPrevention #HeartHealth #Longevity #InsulinResistance #DrLilyJohnston #DrLily #WomenInMedicine #Surgeon #VascularSurgeon #PreventiveMedicine #PADPrevention #HeartAttackRisks #HealthPortfolio #California #SanDiego #Arizona #Virginia #minnesota

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    9 mins
  • GLP-1 Drugs Cut Heart Attack Risk — And It Has Nothing to Do With Weight
    Mar 30 2026

    SELECT trial explained: does semaglutide reduce cardiovascular risk because of weight loss, or is something else going on? In this video, I break down the SELECT trial and the follow-up analysis examining whether the cardiovascular benefit of semaglutide was directly mediated by weight loss. The answer matters, because the data suggest the reduction in major adverse cardiovascular events was not simply a function of people losing more weight.

    I’m a board-certified vascular surgeon focused on cardiometabolic prevention, and in this video I walk through what the SELECT trial actually showed, what the subsequent analysis adds, and why this changes how we think about GLP-1 receptor agonists, obesity, heart disease, and prevention. If you’ve been wondering whether semaglutide’s heart protection is just about the number on the scale, this is where we separate mechanism from marketing.

    In this video, I cover:
    • The SELECT trial design and main cardiovascular outcomes
    • How semaglutide affected heart attack, stroke, and cardiovascular death risk
    • The follow-up mediation analysis on weight loss
    • Why the cardiovascular benefit does not appear to be explained by weight loss alone
    • What this may mean for inflammation, metabolism, and vascular protection
    • How I think about semaglutide clinically in the bigger picture of cardiometabolic health

    If you care about semaglutide, GLP-1 drugs, cardiovascular disease prevention, obesity medicine, insulin resistance, plaque, and the real mechanisms behind cardiometabolic risk reduction, you’re in the right place.

    Question for you: when you think about semaglutide, do you mainly think “weight loss drug,” or has the cardiovascular data changed your view?


    Sign up for more information on my own practice here: https://corsighthealth.com/

    High Quality 3rd-party tested supplements at Fullscript (10% discount): https://us.fullscript.com/welcome/ljohnstonmd/store-start

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    ___________________________
    🧬 About Dr. Lily Johnston

    Dr. Johnston is a double board-certified vascular and general surgeon in San Diego, specializing in metabolic and cardiovascular prevention. She’s the founder of CorSight Health and a passionate advocate for reimagining how medicine approaches chronic disease.

    #MetabolicHealth #CardiovascularPrevention #HeartHealth #Longevity #InsulinResistance #DrLilyJohnston #DrLily #WomenInMedicine #Surgeon #VascularSurgeon #PreventiveMedicine #PADPrevention #HeartAttackRisks #HealthPortfolio #California #SanDiego #Arizona #Virginia #minnesota

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    27 mins
  • What We Get Wrong About Poor Circulation (with Vascular Surgeon Dr. Jackie Majors)
    Mar 23 2026

    When people hear “poor circulation,” they often assume the answer is a procedure. Not so fast. In this episode of Knife Down, Dr. Jacqueline Majors and I talk about when opening a blocked artery helps, when it backfires, and why the real work of saving legs often starts long before the operating room.

    We get into what patients with poor circulation, blocked leg arteries, leg pain with walking, smoking-related vascular disease, and diabetes actually need to know. We talk about when a procedure helps, when it can make things worse, why not every blockage should be opened, and how lifestyle change, medical therapy, and careful decision-making can sometimes save a limb better than another stent.

    We also talk about what vascular surgery training gets right and what it misses, how Dr. Majors built a limb salvage-focused private practice, why strength training matters for vascular patients, and how to help people make meaningful changes without shame, perfectionism, or all-or-nothing thinking.

    Dr. Jacqueline Majors, MD is a board-certified vascular surgeon, Co-Owner, and Director of Limb Salvage at Zenith Vascular & Fibroid Center in Memphis, Tennessee. She is CEO of Vascular Excellence, PLLC, a consulting firm spanning expert witness work and locum tenens. She is also Founder and CEO of AnatomyPad, a patient education and operative planning product. She has performed multiple first-in-state procedures in Tennessee, including absorbable stents, retrievable BTK stents, advanced thrombectomy, and intravascular lithotripsy.

    Dr. Majors is a two-time Castle Connolly Top Doctor and multiple Top Doctor in Tennessee award recipient. She serves as an industry KOL, speaking nationally on drug-coated balloon therapy, intravascular lithotripsy, carotid disease, and limb salvage. She hosts Center of Excellence courses in Memphis, is the Vice Chair of the Young Physicians Association for the Tennessee Medical Association, and serves on the Board of the Memphis Medical Society.

    A former Division I athlete and nationally licensed soccer coach, she brings that same discipline to medicine, business, and patient care. Her philosophy: excellence is not an outcome. It is a discipline.

    Find Dr. Majors here:
    https://www.instagram.com/zenithmemphis/
    https://www.linkedin.com/company/zenith-memphis/
    https://www.facebook.com/zenithmemphis

    This episode is for education only and is not personal medical advice. If you have symptoms of poor circulation, a nonhealing wound, rest pain, or concern for blocked arteries, please talk with your own physician.

    Chapters
    00:00 Introduction
    00:18 Why prevention matters in vascular surgery
    04:07 Nutrition, sleep, stress, and the athlete mindset
    08:07 Why she chose vascular surgery
    10:57 Talking to patients about new procedures
    14:13 What vascular training misses about lifestyle
    16:43 Nutrition philosophy: from “eat healthy” to low-carb Mediterranean
    22:38 Patient stories: saving limbs without rushing to procedure
    27:12 Why not every blocked leg artery should be fixed
    31:24 Why poor circulation is underrecognized
    34:35 Building a limb salvage-focused private practice
    43:24 Social media, physician education, and the modern doctor
    49:59 How Dr. Majors approaches food, exercise, and habit change
    57:05 Walking, strength training, and insulin resistance
    01:01:00 Helping patients who aren’t ready to change
    01:05:44 Smoking, diabetes, and whether all plaque is the same
    01:08:05 What medical management vascular surgeons should own
    01:11:34 How to get screened for poor circulation
    01:13:53 The top 3 ways to prevent blocked leg arteries
    01:15:15 Favorite procedures, resources, and AnatomyPad
    01:19:30 Where to find Dr. Jacqueline Majors

    Sign up for more information on my own practice here: https://corsighthealth.com/

    High Quality 3rd-party tested suppl

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    1 hr and 21 mins